Browsing by Author "Çeliker, Serkan"
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Central tunnel as an alternative allosteric site in glyceraldehyde-3-phosphate-dehydrogenase for potential use as species specific drug targets /
Çeliker, Serkan (Kadir Has Üniversitesi, 2020)İlaç keşif çalışmalarında en yeni yaklaşımlardan biri proteindeki potansiyel allosterik bölgeler için ilaç tasarımıdır. Bu bölgeler enzimlerin aktif bölgelerini doğrudan hedefleyen inhibitörler yerine aktif bölge üzerine ... -
Identification of Alternative Allosteric Sites in Glycolytic Enzymes for Potential Use as Species-Specific Drug Targets
Ayyıldız, Merve; Çeliker, Serkan; Özhelvacı, Fatih; Akten, Ebru Demet (Frontiers Media, 2020)Three allosteric glycolytic enzymes, phosphofructokinase, glyceraldehyde-3 phosphate dehydrogenase and pyruvate kinase, associated with bacterial, parasitic and human species, were explored to identify potential allosteric ...